Transduction of Multiple Nutritional Requirements in Salmonella Typhimurium
نویسندگان
چکیده
منابع مشابه
Transduction by bacteriophage P22 in nonsmooth mutants of Salmonella typhimurium.
The general transducing phage P22 attacks only smooth (S) Salmonella with O antigen 12, determined by the oligosaccharide repeating unit constituting the distal part of the somatic lipopolysaccharide (LPS) side chain; non-S mutants, whose LPS contain few or no O repeating units, appear to be resistant. Auxotrophic non-S mutants of Salmonella typhimurium LT2 were tested as transductional recipie...
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Salmonella is the causative agent of a spectrum of human and animal diseases ranging from gastroenteritis to typhoid fever. It is a food--and water--borne pathogen and infects via ingestion followed by invasion of intestinal epithelial cells and phagocytic cells. In this study we employed a mutational approach to define the nutrients and metabolic pathways required by Salmonella enterica serova...
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The nutritional requirements of the Genus Salmonella, especially of such particular members as S. typhi (1, 2), S, gallinarum and S. pullorum(2), etc, have long been investigated. Salmonella organisms were classified by Hohn et al. (3) into two categories, Ammonium strong and Ammonium weak, according to their ability to grow in the ammonium synthetic medium. In 1946 Lederberg and Tatum(4) studi...
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Epidemic strain Salmonella typhimurium DT104 is characterized by various multiresistance patterns. At least some of the resistance genes are organized as integrons. Resistance genes of DT104 isolates can be efficiently transduced by P22-like phage ES18 and by phage PDT17 which is released by all DT104 isolates so far analyzed. Cotransduction tests demonstrate that the resistance genes, although...
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Four strains of Salmonella typhimurium avirulent for mice were found to be capable of acting as gene acceptors in transduction experiments. An attempt was made to transduce virulence to three strains, using a typical mouse-virulent strain of S. typhimurium as donor. Two of the strains which are adenine-dependent were successfully made virulent by transduction and simultaneously became adeninein...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1952
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.38.9.797